This paper explores the managerial context surrounding fairness promotion using a multi-method examination that employs interviews and a survey of practicing managers. The results of these examinations describe how managers tend to focus their efforts to promote fairness on fairly allocating rewards and responsibilities, accurately and consistently applying organizational policies and providing representation and understanding to their subordinates around key organizational issues. Analyses of the interview and survey data show how managers’ efforts to promote employee development, enact managerial propriety, and (...) demonstrate moral leadership mediate relationships between their fundamental desires to develop positive working relationships with their subordinates and the efforts they make to promote fairness. This paper concludes with a discussion about how this work refines and extends research on how and why managers promote fairness. (shrink)

The landscapes of mammalian genomes are characterized by complex patterns of intersecting and overlapping sense and antisense transcription, giving rise to large numbers of coding and non‐protein‐coding RNAs (ncRNAs). A recent report by Kapranov and colleagues1 describes three potentially novel classes of RNAs located at the very edges of protein‐coding genes. The presence of RNAs from one of these classes appears to be correlated with the expression levels of their associated genes. These results suggest that a proportion of these RNAs (...) might have roles in the cis‐regulation of neighbouring protein‐coding genes' expression. BioEssays 29:1077–1080, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

BackgroundRandomized controlled trials (RCTs) are often complex and expensive to perform. Less than one third achieve planned recruitment targets, follow-up can be labor-intensive, and many have limited real-world generalizability. Designs for RCTs conducted using cohorts and routinely collected health data, including registries, electronic health records, and administrative databases, have been proposed to address these challenges and are being rapidly adopted. These designs, however, are relatively recent innovations, and published RCT reports often do not describe important aspects of their methodology in (...) a standardized way. Our objective is to extend the Consolidated Standards of Reporting Trials (CONSORT) statement with a consensus-driven reporting guideline for RCTs using cohorts and routinely collected health data.MethodsThe development of this CONSORT extension will consist of five phases. Phase 1 (completed) consisted of the project launch, including fundraising, the establishment of a research team, and development of a conceptual framework. In phase 2, a systematic review will be performed to identify publications (1) that describe methods or reporting considerations for RCTs conducted using cohorts and routinely collected health data or (2) that are protocols or report results from such RCTs. An initial “long list” of possible modifications to CONSORT checklist items and possible new items for the reporting guideline will be generated based on the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) and The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statements. Additional possible modifications and new items will be identified based on the results of the systematic review. Phase 3 will consist of a three-round Delphi exercise with methods and content experts to evaluate the “long list” and generate a “short list” of key items. In phase 4, these items will serve as the basis for an in-person consensus meeting to finalize a core set of items to be included in the reporting guideline and checklist. Phase 5 will involve drafting the checklist and elaboration-explanation documents, and dissemination and implementation of the guideline.DiscussionDevelopment of this CONSORT extension will contribute to more transparent reporting of RCTs conducted using cohorts and routinely collected health data. (shrink)

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele (...) is associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

Researchers have suggested that ethical judgments about “right” and “wrong” are the result of deep and thoughtful principles and should therefore be consistent and not influenced by factors, such as language :e94842, 2014b, p. 1). As long as an ethical scenario is understood, individuals’ resolution should not depend on whether the ethical scenario is presented in their native language or in a foreign language. Given the forces of globalization and international convergence, an increasing number of accountants and accounting students (...) are becoming proficient in more than one language, and they are required to interpret and apply complex ethical pronouncements issued by various global standard setters both in their native language and in English. There have been calls in the literature to examine whether subjects make systematically different ethical judgments in a foreign language than in their native language. We contribute to the literature by drawing on culture, linguistics, and psychology research to provide empirical evidence that Chinese subjects are more aggressive in interpreting the concept of control when providing their consolidation reporting recommendations in English than in Simplified Chinese. We applied a 2 × 2 within-subject and between-subject randomized experimental design using a sample of Chinese final year undergraduate accounting students at a leading Chinese university, where accounting courses are taught in both Simplified Chinese and English. Students in our study are proxy for entry-level accounting practitioners. Our findings have implications for the globalized business world and cross-cultural research by challenging the commonly held assumption that an individual’s ethical judgment is consistent in different languages. We suggest that systematically different ethical judgments in native and foreign languages needs to be recognized. (shrink)

Stuart Hameroff opens with an extended and updated exposition of the Penrose/Hameroff Orch-OR model, and subsequently addresses recent criticisms of quantum approaches to the brain. Evan Walker presents his view on consciousness from the perspective of a new approach to the integration of quantum theory and relativity. Friedrich Beck elaborates on the Beck/Eccles quantum approach to consciousness. Karl Pribram puts the holographic view on consciousness in perspective of his life long work. Peter Marcer and Edgar Mitchell explain the relevance (...) of quantum holography for consciousness. Gordon Globus discusses the relation between postmodern philosophical theories and quantum consciousness. Chris Clarke develops a theory in terms of a specific type of formal logic to reconcile the phenomenology of consciousness with the physical world. Ilya Prigogine summarizes his view on complexity, and on the future of quantum theory, which goes beyond the present formalism, and goes on to comment on the problem of consciousness. Matti Pitkanen identifies the place for consciousness in a unifying topological geometro-dynamics theory. Colin McGinn argues against classical materialism. Dick Bierman gives an overview of anomalous phenomena. He identifies a decline effect, and discusses different possible interpretations. Philip Van Loocke closes the volume with a discussion on how deep teleology in cellular systems may relate to consciousness. (shrink)

In most decision-making situations, there is a plethora of information potentially available to people. Deciding what information to gather and what to ignore is no small feat. How do decision makers determine in what sequence to collect information and when to stop? In two experiments, we administered a version of the German cities task developed by Gigerenzer and Goldstein (1996), in which participants had to decide which of two cities had the larger population. Decision makers were not provided with the (...) names of the cities, but they were able to collect different kinds of cues for both response alternatives (e.g., “Does this city have a university?”) before making a decision. Our experiments differed in whether participants were free to determine the number of cues they examined. We demonstrate that a novel model, using hierarchical latent mixtures and Bayesian inference (Lee & Newell, 2011) provides a more complete description of the data from both experiments than simple conventional strategies, such as the take–the–best or the Weighted Additive heuristics. (shrink)

The paper is concerned with the existence and asymptotic character of the nonlinear boundary value problemdG/dt=F ¦ –¦dF/dt=gG =k 1,G=k 2 as ¦– ¦ o+ The discussion is related to the problem of particle-number fluctuations in the theory of cosmic radiation andG andF denote respectively the probability generating functions for the electron distribution in an electron-initiated and a photon-initiated shower.A solution of the system satisfying the boundary conditions is constructed so that specified limiting conditions are fulfilled.

In the Gorgias, Socrates claims to practice the true art of politics, but the peculiar politics he practices involves cultivating in each individual he encounters an erotic desire to live a life animated by the ideals of justice, beauty and the good. Socratic and Platonic Political Philosophy demonstrates that what Socrates sought to do with those he encountered, Platonic writing attempts to do with readers. Christopher P. Long's attentive readings of the Protagoras, Gorgias, Phaedo, Apology, and Phaedrus invite us (...) to cultivate the habits of thinking and responding that mark the practices of both Socratic and Platonic politics. Platonic political writing is here experienced in a new way as the contours of a politics of reading emerges in which the community of readers is called to consider how a commitment to speaking the truth and acting toward justice can enrich our lives together. (shrink)

Agroecology has been proposed as a key building block for food sovereignty. This article examines the meaning, practices and potentials of ‘transformative agroecology learning’ as a collective strategy for food system transformation. Our study is based on our qualitative and action research with the European Coordination of Via Campesina to develop the European Agroecology Knowledge Exchange Network. This network is linked to the global network of La Via Campesina and builds on the strong experiences and traditions of popular education in (...) Latin American peasant movements. Rather than focusing on agroecology education as a process of individual learning, we analyse how a transformative agroecology education can be strengthened as a critical repertoire of action used by social movements to advance food sovereignty. Our analysis contributes a new theory of transformative agroecology learning based on four key characteristics or qualities: horizontalism; diálogo de saberes ; combining practical and political knowledge; and building social movement networks. While these different elements of transformative agroecology learning were present across EAKEN, they were unevenly developed and, in many cases, not systematized. The framework can help to strategically and reflexively systematize and strengthen a transformative agroecology learning approach as a key building block for food sovereignty. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Rhetoric 34.4 (2001) 292-307 [Access article in PDF] The Rhetoric of the Geometrical Method Spinoza's Double Strategy Christopher P. Long A double strategy may be apprehended in the first definitions, axioms and propositions of Spinoza's Ethics: the one is rhetorical, the other, systematic. Insofar as these opening passages constitute a geometrical argument that leads ultimately to the strict monism that lies at the heart of Spinoza's (...) philosophy, they function systematically as grounding principles. However, insofar as they are designed to uncover errors at the heart of the Cartesian system, they function rhetorically as a critique of Descartes's equivocal theory of substance. The geometrical mode of presentation lends an aura of necessity to the systematic strategy and tends to eclipse the rhetorical strategy that functions as a critique of Cartesian dualism. 1 To this extent, the systematic strategy itself functions rhetorically. On the other hand, to the extent that any seventeenth-century attempt to establish a monistic system would inevitably have had to involve a critique of Cartesian dualism, the rhetorical strategy itself functions systematically. Thus, although two distinct strategies are simultaneously discernible in the opening passages of the Ethics, the two work together, each arguing on a different front, to establish Spinoza's monism. By focusing on the rhetorical side of this double strategy, the underlying nature of Spinoza's critique of Descartes can be clarified and certain gaps in the systematic, geometrical argument for monism can be explained. Descartes's theory of substance The rhetorical strategy Spinoza employs at the outset of the Ethics involves a brilliant use of equivocation and ambiguity designed to draw a reader dedicated to Cartesian dualism into the heart of an argument designed to [End Page 292] undermine this dualism itself. The impetus behind this rhetorical critique is surely Spinoza's dissatisfaction with Descartes's theory of substance. 1. Descartes's equivocation Descartes's theory rests upon a fundamental equivocation: on the one hand, the term "substance" is meant strictly to designate that which is absolutely self-sufficient, namely, God; on the other hand, Descartes allows for a weaker understanding of substance, which pertains to those things (specifically res cogitans and res extensa) that require only the concurrence of God in order to exist (Principles I, 51-52; AT VIIIA24-25). 2 Thus, for Descartes, although God is, strictly speaking, the only substance, there remains a sense in which both res cogitans and res extensa may be understood as substances as well.Ultimately, this equivocal understanding of substance may be traced to a tension internal to Descartes between the Aristotelian notion of substance as underlying subject and the seventeenth-century mutation of that notion, which came to be defined in terms of causal self-sufficiency. 3 Jonathan Bennett traces the source of this mutation back to the view held by Aristotle that the existence of some property depends upon its being instantiated--that is, there can be no courage unless there exists someone courageous. He continues his interesting argument thus: This suggests that there is a relation of dependence running from properties to the things that have them and not conversely. The dependence would be logical: the thesis must be that "existent but uninstantiated property" is conceptually defective, not merely contrary to physics. Thus, one mark of a genuine thing, or substance, is its not being logically dependent for its existence on anything else. (Bennett 1984, 56) The development of this line of thinking leads to the conception of substance we find both in Descartes's Principles and in Spinoza's Ethics, namely, that a substance must not causally depend on anything outside of itself for its existence. 4 However, with Descartes, what emerges out of this tradition is a hybrid understanding of substance in which the term "substance" is not reserved simply for that which is utterly self-sufficient (God), but extends to those things that depend only upon the concurrence of God for their existence (rescogitans and resextensa). This bifurcated understanding of substance seems to stem from the distinction at work in [End Page 293] Aristotle... (shrink)

Nearly fifty years after the incorporation of the International Society for Knowledge Organization and the introduction of its formal scientific journal Knowledge Organization, a comprehensive encyclopedia of the domain appeared. The practice of domain analysis for knowledge organization, twenty years after its introduction as a core methodology, has created the largest corpus of theoretical knowledge in the domain analysis of knowledge organization itself. A substantial body of research data, therefore, is available in the corpus of articles and conference papers reporting (...) on the epistemological and ontological pillars of the science of knowledge organization. This paper is a report on the evolution of a formal taxonomy of knowledge organization, which is a product of an exhaustive meta-analysis of the KO domain. Our team compiled the corpus of twenty-nine formal published analyses together with key formative historical documents. We then analyzed the corpus thematically, bibliographically, and using co-word analysis to extract key concepts and the underlying faceted conceptual infrastructure. The taxonomy itself is faceted and is linked where possible to published definitions in the KO literature and as well as to the online ISKO Encyclopedia of Knowledge Organization. A dynamic project, the taxonomy will be maintained as linked open data and will grow as emergent research contributes new concepts or generates new facets. (shrink)

A novel rereading of the relationship between ethics and ontology in Aristotle.

The emphasis in most process-oriented models of argumentation is placed heavily upon analysis of dialogue. The current work puts forward an account which examines the argumentation involved in persuasive monologue, drawing upon commitment-based theories of dialogue. The various differences between monologue and dialogue are discussed, with particular reference to the possibility of designing a monologue game in which commitments are dynamically incurred and updated as the monologue is created. Finally, the computational advantages of adopting such an approach are explored in (...) the context of an existing architecture for the generation of natural language arguments. (shrink)

This book articulates the nature of truth as a cooperative activity between human beings and the natural world that is rooted in our endeavors to do justice to the nature of things.

Following Birkhoff and von Neumann, quantum logic has traditionally been based on the lattice of closed linear subspaces of some Hubert space, or, more generally, on the lattice of projections in a von Neumann algebra A. Unfortunately, the logical interpretation of these lattices is impaired by their nondistributivity and by various other problems. We show that a possible resolution of these difficulties, suggested by the ideas of Bohr, emerges if instead of single projections one considers elementary propositions to be families (...) of projections indexed by a partially ordered set C(A) of appropriate commutative subalgebras of A. In fact, to achieve both maximal generality and ease of use within topos theory, we assume that A is a so-called Rickart C*-algebra and that C(A) consists of all unital commutative Rickart C*-subalgebras of A. Such families of projections form a Hey ting algebra in a natural way, so that the associated propositional logic is intuitionistic: distributivity is recovered at the expense of the law of the excluded middle. Subsequently, generalizing an earlier computation for n x n matrices, we prove that the Heyting algebra thus associated to A arises as a basis for the internal Gelfand spectrum (in the sense of Banaschewski-Mulvey) of the "Bohrification" A̱ of A, which is a commutative Rickart C*-algebra in the topos of functors from C(A) to the category of sets. We explain the relationship of this construction to partial Boolean algebras and Bruns-Lakser completions. Finally, we establish a connection between probability measures on the lattice of projections on a Hubert space H and probability valuations on the internal Gelfand spectrum of A̱ for A = B(H). (shrink)

Genetic studies in the social sciences could be augmented through the additional consideration of functional (transcriptome, methylome, metabolome) and/or multimodal genetic data when attempting to understand the genetics of social phenomena. Understanding the biological pathways linking genetics and the environment will allow scientists to better evaluate the functional importance of polygenic scores.

At the beginning of his book, Methode und Beweisziel im ersten Buch der “Physikvorlesung” des Aristoteles, Johannes Fritsche announces that the theme of the work is to be more or less Aristotle’s Physics. It is to be less about the Physics insofar as it treats only two sentences of its first book—the first sentence of chapter one and a sentence taken from its decisive seventh chapter. It is to be more about the Physics insofar as it explicates these two sentences (...) in order to establish the principle according to which the entire Physics is constructed. Fritsche’s book is impressive both in its breadth and its depth. He situates his own position within a broad historical tradition by addressing both ancient commentators, like Simplicius and Philoponus, and modern commentators, like Wieland and Guzzoni. He argues, however, the unpopular position that the books of the Physics do have a systematic relationship to one another, that they are not merely an amalgamation of individual thoughts on the general subject of natural philosophy. One of the most intriguing aspects of Fritsche’s account is his suggestion that the main goal of the first two books of the Physics is to establish the condition for the possibility that there are principles of natural beings. In this, he distinguishes his own position from many in the tradition who claim that Aristotle assumes the existence of such principles without ever actually arguing for them. (shrink)

Scholars often assume that Aristotle uses the terms morphē and eidos interchangeably. Translators of Aristotle's works rarely feel the need to carry the distinctionbetween these two Greek terms over into English. This article challenges the orthodox view that morphē and eidos are synonymous. Careful analysis of texts fromthe Categories, Physics, and Metaphysics in which these terms appear in close proximity reveals a fundamental tension of Aristotle's thinking concerning the being of natural beings. Morphē designates the form as inseparable from the (...) matter in which it inheres, while eidos, because it is more easily separated from matter, is the vocabulary used to determine form as the ontological principle of the composite individual. The tension between morphē and eidos—between form as irreducibly immanent and yet somehow separate—is then shown to animate Aristotle's phenomenological approach to the being of natural beings. This approach is most clearly enacted in Aristotle's biology, a consideration of which concludes the essay. (shrink)

Although laughter plays an essential part in emotional vocal communication, little is known about the acoustical correlates that encode different emotional dimensions. In this study we examined the acoustical structure of laughter sounds differing along four emotional dimensions: arousal, dominance, sender's valence, and receiver-directed valence. Correlation of 43 acoustic parameters with individual emotional dimensions revealed that each emotional dimension was associated with a number of vocal cues. Common patterns of cues were found with emotional expression in speech, supporting the hypothesis (...) of a common underlying mechanism for the vocal expression of emotions. (shrink)

This essay charts the parallel growth of Newman's theory of doctrinal development, and infallibility within that doctrinal development, with its author's movement from a via media in Anglicanism to recognition of the truth in the Roman Church. This essay analyzes the theological need for a theory of doctrinal development, the failure of Newman's via media project, and his role as a creative theologian. Then this essay examines in detailed Newman's 1845 Essay on the Development of Christian Doctrine, looking specifically at (...) the second section of the second chapter, ‘On the Probability of a Developing Authority in Christianity.’ The main body of the paper treats the expansion of the scope and feasibility of infallibility in Newman's 1845 Essay. (shrink)

At least since the appearance of Aristotle’s Politics, Plato’s Republic has been read as arguing for a politics of unity in which difference is understood as a threat to the polis. By focusing on the musical imagery of the Republic, and specifically on its compositional organization around three ‘preludes’, this essay seeks an understanding of Socratic politics that moves beyond the hypothesis of unity. In the first ‘prelude’, Thrasymachus and his insistence that justice is the self-interest of the stronger threatens (...) to subject the harmony of the community to the tyrannical whims of the individual. In the second, the perfected justice of Adeimantus’s city threatens to destroy the erotic rhythm of difference that is the very condition for the possibility of the polis. It is only in the song of dialectic, which itself is called a ‘prelude’, that the tension between the rhythm of plurality and the rational homophony of unity is dynamically tuned in such a way that both the anarchic politics of self-interest and the totalitarian politics of rationalized oppression are equally muted. This conception of politics is embodied in the relationship that emerges between Glaucon and Socrates. Ultimately, the true political community is established here, between rational, erotic individuals seeking justice in concrete, living dialogue. (shrink)

This essay articulates the differences and suggests the similarities between the practices of Socratic political speaking and those of Platonic political writing. The essay delineates Socratic speaking and Platonic writing as both erotically oriented toward ideals capable of transforming the lives of individuals and their relationships with one another. Besides it shows that in the Protagoras the practices of Socratic political speaking are concerned less with Protagoras than with the individual young man, Hippocrates. In the Phaedo, this ideal of a (...) Socrates is amplified in such a way that Platonic writing itself emerges as capable of doing with readers what Socratic speaking did with those he encountered. Socrates is the Platonic political ideal. The result is a picture of the transformative political power of Socratic speaking and Platonic writing both. El ensayo articula diferencias y sugiere similitudes entre las prácticas del diálogo político de Sócrates y aquellas de la escritura política de Platón. Propone, además, que tanto el diálogo socrático como la escritura platónica se orientan eróticamente hacia ideales capaces de transformar las vidas de los individuos y sus relaciones. Demuestra que en el Protágoras las prácticas del diálogo socrático se ocupan menos de Protágoras que del joven Hipócrates. En el Fedón, este ideal de Sócrates se amplía de tal manera que la misma escritura platónica aparece como capaz de hacer con los lectores lo que el diálogo de Sócrates hacía con sus interlocutores. Sócrates es el ideal político platónico. El resultado es una visión del poder de transformación política tanto del diálogo socrático como de la escritura platónica. (shrink)

Ontology has been traditionally guided by sophia, a form of knowledge directed toward that which is eternal, permanent, necessary. This tradition finds an important early expression in the philosophical ontology of Aristotle. Yet in the Nicomachean Ethics, Aristotle's intense concern to do justice to the world of finite contingency leads him to develop a mode of knowledge, phronsis, that implicitly challenges the hegemony of sophia and the economy of values on which it depends. Following in the tradition of the early (...) Heidegger's recognition of the ontological significance of Aristotle's Ethics and of Gadamer's appropriation of phronsis for hermeneutics, this article argues that an ontology guided by phronsis is preferable to one governed by sophia. Specifically, it suggests that by taking sophia as its paradigm, traditional philosophical ontology has historically been determined by a kind of knowledge that is incapable of critically considering the concrete historico-ethico-political conditions of its own deployment. This critique of sophia is accomplished by uncovering the economy of values that led Aristotle to privilege sophia over phronsis. It is intended to open up the possibility of developing an ontology of finite contingency based on phronsis. Such an ontology, because it is guided by and must remain responsible to the concrete individual with which it is engaged, would be ethical at its very core. (shrink)

Many studies have argued for distinct but complementary contributions from each hemisphere in the control of movements to visual targets. Investigators have attempted to extend observations from patients with unilateral left- and right-hemisphere damage, to those using neurologically-intact participants, by assuming that each hand has privileged access to the contralateral hemisphere. Previous attempts to illustrate right hemispheric contributions to the control of aiming have focussed on increasing the spatial demands of an aiming task, to attenuate the typical right hand advantages, (...) to try to enhance a left hand reaction time advantage in right-handed participants. These early attempts have not been successful. The present study circumnavigates some of the theoretical and methodological difficulties of some of the earlier experiments, by using three different tasks linked directly to specialized functions of the right hemisphere: bisecting, the gap effect, and visuospatial localization. None of these tasks were effective in reducing the magnitude of left hand reaction time advantages in right handers. Results are discussed in terms of alternatives to right hemispheric functional explanations of the effect, the one-dimensional nature of our target arrays, power and precision given the size of the left hand RT effect, and the utility of examining the proportions of participants who show these effects, rather than exclusive reliance on measures of central tendency and their associated null hypothesis significance tests. (shrink)

In Plato’s Protagoras Alcibiades plays the role of Hermes, the ‘ambassador god,’ who helps lead Socrates’ conversation with Protagoras through a crisis of dialogue that threatens to destroy the community of education established by the dialogue itself. By tracing the moments when Alcibiades intervenes in the conversation, we are led to an understanding of Socratic politics as always concerned with the course of the life of an individual and the proper time in which it might be turned toward the question (...) of justice and the good. (shrink)

On Philosophy and Philosophers is a volume of unpublished philosophical papers by Richard Rorty, a central figure in late-twentieth-century intellectual debates and a primary force behind the resurgence of American pragmatism. The first collection of new work to appear since his death in 2007, these previously unseen papers advance novel views on metaphysics, ethics, epistemology, philosophical semantics and the social role of philosophy, critically engaging canonical and contemporary figures from Plato and Kant to Kripke and Brandom. This book's diverse offerings, (...) which include technical essays written for specialists and popular lectures, refine our understanding of Rorty's perspective and demonstrate the ongoing relevance of the iconoclastic American philosopher's ground-breaking thought. An introduction by the editors highlights the papers' original insights and contributions to contemporary debates. (shrink)

Little is known about distance processing in patients with posterior brain damage. Although many investigators have claimed that distance estimates are normal or abnormal in some of these patients, many of these observations were made informally and the examiners often asked for relative, and not absolute, distance estimates. The present investigation served two purposes. First, we wanted to contrast the use of distance information in peripersonal space for perceptual report as opposed to visuomotor control in our visual form agnosic patient, (...) DF. Second, we wanted to see to what extent her abilities to process distance cues were dependent on binocular vision, in light of Milner et al.'s (1991) observations of preserved stereopsis in DF, and Dijkerman et al.'s (1996) and Marotta et al.'s (1997) observations that her visual guidance of grasping may be particularly dependent on binocular vision of the target. We hypothesized that DF's visuomotor responses would show normal sensitivity to target distance, while her perceptual estimates would not. In the first experiment, we required DF and two age- and sex-matched control subjects to reach out and grasp black cubes placed at varying distances, or to estimate the distance of the cubes from the hand starting position without making a reaching movement. In the second experiment, we required DF and two age-matched control subjects to point as rapidly and accurately as possible to small LED targets which differed in spatial location, under binocular and monocular conditions. The results showed that, relative to the control subjects, DF's grasping movements produced normal peak velocity-distance scaling-when she reached for blocks which varied in depth or pointed to LED targets which were presented at different distances in depth. In contrast, in the cube experiment, her verbal estimates of object distance were poorly scaled, although they improved slightly under the binocular conditions. The results are discussed in terms of current theories of processing streams in extrastriate visual cortex and the distinction between categorical and coordinate spatial processing. (shrink)